Camila Góes Araújo
Kevin Luiz Lopes-Delphino
Denise Tostes Oliveira
Melyna Marques de Almeida
Agnes Assao

ABSTRACT
A rising incidence of oral squamous cell carcinoma (OSCC) in younger patients without
traditional risk factors has been observed, with the tongue being the most commonly
affected site in this population. This study aims to report a case of tongue squamous cell
carcinoma in a young patient. Case Report: A 45-year-old male driver presented at the
university dental clinic with the chief complaint of a nodule on the tongue. During the
anamnesis, the patient reported no addictions, such as smoking or alcohol consumption.
Intraoral examination revealed a painless nodule on the lateral and posterior border of the
tongue, unrelated to trauma, with approximately one month of evolution. An incisional
biopsy was performed, and histopathological examination confirmed a diagnosis of
tongue squamous cell carcinoma. Although uncommon, this case highlights a different
profile of the disease, affecting young patients without typical risk factors, with an
uncertain prognosis. Genetic influences may contribute to the etiopathogenesis of the
disease, but further investigation into new associated risk factors is necessary given the
increasing number of cases in patients without traditional risk factors. It is crucial to raise
awareness among dentists regarding the importance of a detailed analysis of oral lesions,
as early diagnosis directly impacts prognosis.

Key-words: Tongue tumors. Squamous cell carcinoma. Adults.