Stephanie Braga Gonçalves da Silva
Paulo Guilherme de Oliveira Salles
Iracema Maria Ribeiro da Fonseca
Thalia Rodrigues de Souza Zozimo
Débora Cristina de Freitas Batista
Carolina Pereira de Melo
ABSTRACT
Despite the low prevalence, ovarian cancer has high mortality. More common in elderly patients, is mostly diagnosed late, which leads to high recurrence and a low five-years-disease-free-survival Carcinoma is the most common type, and the high grade serous carcinoma (HGSC) subtype stands out in terms of aggressiveness. Whereas genetic mutations would be responsible for this difference, it was proposed a tumor classification model, which considers the main genetic changes found. Here we describe the genetic associations observed in young patient with HGSC and her clinical outcome.